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Abortion care

  • NICE guideline
  • Reference number: NG140
  • Published:  25 September 2019
  • Last updated:  27 May 2025
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Research recommendations coming out of this guidance

  • What is the optimal antibiotic prophylaxis regimen for women who are having a surgical abortion?

  • What are the most effective and acceptable methods of cervical priming before dilatation and evacuation after 16+0 weeks' gestation?

  • Should women having a surgical abortion up to and including 10+0 weeks' gestation have anti-D prophylaxis if they are RhD (or D) negative?

  • For women who are having medical abortion between 10+1 and 12+0 weeks, what is the efficacy and acceptability of expulsion at home compared with expulsion in a clinical setting?

  • What local anaesthetic techniques are most effective for women having surgical abortion?

  • What is the effectiveness and safety of regimens using mifepristone and misoprostol for women who are having medical abortion after 23+6 weeks' gestation, particularly for those who have had a previous caesarean section or uterine surgery?

  • What is the optimal regimen for general anaesthesia for women having surgical abortion?

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