Evidence reviews - June 2022
The following documents contain the evidence that was used to develop the recommendations:
- Patient information
- What signs and symptoms indicate gout as a possible diagnosis?
- What are the most accurate and cost-effective approaches to diagnosing gout, in particular serum urate level compared with joint aspiration?
- Pharmacological and non-pharmacological interventions for managing gout flares
- Which people with gout should be offered a urate-lowering therapy
- Timing of urate-lowering therapy in relation to a flare in people with gout
- Urate-lowering therapies for the long-term management of gout
- Colchicine, NSAIDs, corticosteroids and IL-1 inhibitors for the prevention of gout flares during the initiation or titration of urate-lowering therapy
- Diet and lifestyle modifications for managing gout
- Treat-to-target management
- The best serum urate level target to use when treating-to-target in gout?
- Optimum frequency of monitoring
- Follow-up for people with gout after a gout flare
- Referral to specialist services
- Surgical excision of tophi
Other supporting evidence
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