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Adrenal insufficiency: identification and management

  • NICE guideline
  • Reference number: NG243
  • Published:  28 August 2024
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Research recommendations coming out of this guidance

  • What is the clinical and cost effectiveness of salivary cortisone or cortisol to identify people with adrenal insufficiency?

  • In people at risk of adrenal insufficiency because of prolonged glucocorticoid use, what is the best way to manage glucocorticoid withdrawal when they are no longer needed?

  • What increases the risk of adrenal crisis and adverse hospital outcomes in people taking long-term corticosteroids?

  • What is the clinical and cost effectiveness of glucocorticoids for the routine management of secondary and tertiary adrenal insufficiency?

  • What is the clinical and cost effectiveness of postoperative glucocorticoids for people with, or at risk of, adrenal insufficiency having inpatient invasive procedures?

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