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Published guidance, NICE advice and quality standards
Title
Reference number
Published
Last updated
Isatuximab in combination for untreated multiple myeloma when a stem cell transplant is unsuitable
TA1098
24 September 2025
24 September 2025
Enfortumab vedotin with pembrolizumab for untreated unresectable or metastatic urothelial cancer when platinum-based chemotherapy is suitable
TA1097
11 September 2025
11 September 2025
Benralizumab for treating relapsing or refractory eosinophilic granulomatosis with polyangiitis
TA1096
3 September 2025
3 September 2025
Tirzepatide for managing overweight and obesity
TA1026
23 December 2024
1 September 2025
Tirzepatide for treating type 2 diabetes
TA924
25 October 2023
1 September 2025
Guselkumab for treating moderately to severely active ulcerative colitis
TA1094
28 August 2025
28 August 2025
Guselkumab for previously treated moderately to severely active Crohn's disease
TA1095
28 August 2025
28 August 2025
Idebenone for treating visual impairment in Leber's hereditary optic neuropathy in people 12 years and over
TA1093
28 August 2025
28 August 2025
Pembrolizumab with carboplatin and paclitaxel for untreated primary advanced or recurrent endometrial cancer
TA1092
27 August 2025
27 August 2025
Tarlatamab for extensive-stage small-cell lung cancer after 2 or more treatments
TA1091
20 August 2025
20 August 2025
Durvalumab with tremelimumab for untreated advanced or unresectable hepatocellular carcinoma
TA1090
19 August 2025
19 August 2025
Sacituzumab govitecan for treating hormone receptor-positive HER2-negative metastatic breast cancer after 2 or more treatments (terminated appraisal)
TA1089
13 August 2025
13 August 2025
Ruxolitinib cream for treating non-segmental vitiligo in people 12 years and over
TA1088
13 August 2025
13 August 2025
Ribociclib with an aromatase inhibitor for adjuvant treatment of hormone receptor-positive HER2-negative early breast cancer at high risk of recurrence
TA1086
6 August 2025
6 August 2025
Betula verrucosa for treating moderate to severe allergic rhinitis or conjunctivitis caused by tree pollen
TA1087
6 August 2025
6 August 2025
Vanzacaftor-tezacaftor-deutivacaftor for treating cystic fibrosis with 1 or more F508del mutations in the CFTR gene in people 6 years and over
TA1085
30 July 2025
30 July 2025
Cenobamate for treating focal onset seizures in epilepsy
TA753
15 December 2021
24 July 2025
Letermovir for preventing cytomegalovirus infection after a kidney transplant (terminated appraisal)
TA1082
23 July 2025
23 July 2025
Lisocabtagene maraleucel for treating relapsed or refractory aggressive B-cell non-Hodgkin lymphoma after 1 systemic treatment when a stem cell transplant is unsuitable (terminated appraisal)
TA1083
23 July 2025
23 July 2025
Idecabtagene vicleucel for treating relapsed or refractory multiple myeloma after 2 to 4 treatments (terminated appraisal)
TA1084
23 July 2025
23 July 2025
Fruquintinib for previously treated metastatic colorectal cancer
TA1079
23 July 2025
23 July 2025
Zanubrutinib for treating relapsed or refractory mantle cell lymphoma
TA1081
10 July 2025
10 July 2025
Mirikizumab for previously treated moderately to severely active Crohn's disease
TA1080
10 July 2025
10 July 2025
Dapagliflozin for treating chronic kidney disease
TA1075
2 July 2025
2 July 2025
Adagrasib for previously treated KRAS G12C mutation-positive advanced non-small-cell lung cancer (terminated appraisal)
TA1076
2 July 2025
2 July 2025
Nemolizumab for treating moderate to severe atopic dermatitis in people 12 years and over
TA1077
2 July 2025
2 July 2025
Fosdenopterin for treating molybdenum cofactor deficiency type A (terminated appraisal)
TA1078
25 June 2025
25 June 2025
Sparsentan for treating primary IgA nephropathy
TA1074
25 June 2025
25 June 2025
Marstacimab for treating severe haemophilia A or B in people 12 years and over without anti-factor antibodies
TA1073
24 June 2025
24 June 2025
Atezolizumab for adjuvant treatment of resected non-small-cell lung cancer
TA1071
19 June 2025
19 June 2025
Tislelizumab for treating advanced non-small-cell lung cancer after platinum-based chemotherapy (terminated appraisal)
TA1072
19 June 2025
19 June 2025
Spesolimab for treating generalised pustular psoriasis flares
TA1070
18 June 2025
18 June 2025
Linzagolix for treating symptoms of endometriosis
TA1067
4 June 2025
4 June 2025
Efgartigimod for treating antibody-positive generalised myasthenia gravis
TA1069
4 June 2025
4 June 2025
Somapacitan for treating growth hormone deficiency in people 3 to 17 years
TA1066
3 June 2025
3 June 2025
Tislelizumab for treating unresectable advanced oesophageal squamous cell cancer after platinum-based chemotherapy (terminated appraisal)
TA1068
29 May 2025
29 May 2025
Nivolumab plus ipilimumab for untreated unresectable or metastatic colorectal cancer with high microsatellite instability or mismatch repair deficiency
TA1065
28 May 2025
28 May 2025
Dostarlimab with platinum-based chemotherapy for treating primary advanced or recurrent endometrial cancer with high microsatellite instability or mismatch repair deficiency
TA1064
22 May 2025
22 May 2025
Capivasertib with fulvestrant for treating hormone receptor-positive HER2-negative advanced breast cancer after endocrine treatment
TA1063
15 May 2025
15 May 2025
Erdafitinib for treating unresectable or metastatic urothelial cancer with FGFR3 alterations after a PD-1 or PD-L1 inhibitor
TA1062
12 May 2025
12 May 2025
Osimertinib with pemetrexed and platinum-based chemotherapy for untreated EGFR mutation-positive advanced non-small-cell lung cancer
TA1060
8 May 2025
8 May 2025
Brentuximab vedotin in combination for untreated stage 3 or 4 CD30-positive Hodgkin lymphoma
TA1059
7 May 2025
7 May 2025
Omaveloxolone for treating Friedreich's ataxia in people 16 years and over (terminated appraisal)
TA1061
6 May 2025
6 May 2025
Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19
TA878
29 March 2023
1 May 2025
Tislelizumab in combination for untreated advanced non-small-cell lung cancer (terminated appraisal)
TA1058
23 April 2025
23 April 2025
Rucaparib for maintenance treatment of advanced ovarian, fallopian tube and peritoneal cancer after response to first-line platinum-based chemotherapy
TA1055
16 April 2025
16 April 2025
Molnupiravir for treating COVID-19
TA1056
16 April 2025
16 April 2025
Relugolix–estradiol–norethisterone for treating symptoms of endometriosis
TA1057
16 April 2025
16 April 2025
Cladribine for treating active relapsing forms of multiple sclerosis
TA1053
15 April 2025
15 April 2025
Ruxolitinib for treating acute graft versus host disease that responds inadequately to corticosteroids in people 12 years and over
TA1054
15 April 2025
15 April 2025
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