2 Information about fruquintinib

Marketing authorisation indication

2.1

Fruquintinib (Fruzaqla, Takeda) is indicated for 'the treatment of adult patients with metastatic colorectal cancer (mCRC) who have been previously treated with available therapies, including fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, with or without an anti-VEGF therapy, and, if RAS wildtype and medically appropriate, an anti-EGFR therapy'.

Dosage in the marketing authorisation

Price

2.3

The list price of fruquintinib is £3,950.00 per 21‑pack of 5‑mg capsules and £790.00 per 21‑pack of 1‑mg capsules (excluding VAT; BNF online accessed June 2025).

2.4

The company has a commercial arrangement. This makes fruquintinib available to the NHS with a discount. The size of the discount is commercial in confidence.

Carbon Reduction Plan