2 Information about tirzepatide

Marketing authorisation indication

2.1

Tirzepatide (Mounjaro, Eli Lilly) is indicated for 'the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise

  • as monotherapy when metformin is considered inappropriate due to intolerance or contraindications

  • in addition to other medicinal products for the treatment of diabetes'.

Dosage in the marketing authorisation

Price

2.3

The list prices of tirzepatide (excluding VAT; company communication) for a 4-week supply of pre-filled pen devices for subcutaneous injection are:

  • £133.00 for 2.5 mg 

  • £180.00 for 5 mg 

  • £255.00 for 7.5 mg and 10 mg  

  • £330.00 for 12.5 mg and 15 mg.

2.4

The company has a commercial arrangement. This makes tirzepatide available to the NHS at a cost-effective price determined by NICE. The details of this arrangement are commercial in confidence.