IMI and H2020 Grant funded projects
We are actively involved in a range of methodological research and other projects.
Development and Harmonisation of Methodologies for Assessing Digital Health Technologies in Europe (ASSESS-DHT)
ASSESS-DHT is a European project that aims to increase the adoption of trustworthy and effective digital health technologies (DHTs) across Europe. The project will address the challenges with assessing DHTs by streamlining existing methods and developing a new assessment framework and toolkit. As a partner in the ASSESS-DHT consortium, NICE is leading the development of a European tool that will help developers of DHTs to identify evidence gaps and optimise their evidence development plans. We are also working with partners to develop the interim manual for DHT assessment and pilot its use in assessing an artificial intelligence (AI)-based digital health application.
Support the Utilisation of Sustainable and Tailored Innovative methods for HTA (SUSTAIN-HTA)
The aim of SUSTAIN-HTA is to support the use of innovative methods for European health technology assessment (HTA). It will generate a framework to continuously understand the most pressing needs of HTA bodies, and identify cutting-edge research, methods and tools to address those needs. It will also establish support for HTA organisations to implement new methods. NICE will lead on tasks to review the methods used in existing HTA practices in Europe and prioritise areas where innovative methods and tools should be implemented or developed further.
Revolutionising Alzheimer's Disease Detection and Treatment Across Europe (AD-RIDDLE)
AD-RIDDLE aims to bridge the gap between Alzheimer's research, implementation science and precision medicine. The project will offer healthcare professionals a suite of validated solutions for timely detection and diagnosis of Alzheimer's disease and dementias, to match individuals with the right interventions at the right time, enabling people to better understand what they can do to reduce risk and prevent cognitive decline.
European Digital Health Technology Assessment (EDiHTA)
The aim of EDiHTA is to develop a HTA framework for Digital Health Technologies (DHTs) that integrates existing assessment domains and methods with new ones to inform decision-making. An online platform will allow HTA assessments to be performed digitally in a standardised format that can be customised according to the type and lifecycle stage of the DHT and decision-making process. The digital framework will be piloted in five major European hospitals and through an open piloting scheme with European DHT developers.
PREDICTOM: Early Dementia Detection
PREDICTOM will aim to develop an Artificial Intelligence (AI) screening platform that can identify individuals at risk of developing dementia, even before symptoms manifest. NICE’s role in the project will be to assess current clinical guidelines on early dementia and support the development of recommendations for future guidelines based on the potential step-change in dementia detection intended by the project.
EHDEN: European Health Data and Evidence Network
The EHDEN project aims to set up a European federated network of data sources standardised to a common data model.
The network will enable observational research and the generation of high quality, real world evidence through open collaboration.
ERA4TB: a European Regimen Accelerator for Tuberculosis
The ERA4TB project's main objective is to create a European open platform to accelerate the development of new regimens for the treatment of tuberculosis. The project consortium will do this through a new community-focused platform on tuberculosis translational research and knowledge integration.
During the project, NICE will act as an interface with key stakeholders to maximise uptake and impact of ERA4TB's results. The stakeholders are mainly:
HTA agencies
regulatory authorities
patients.
The project activity will complement our ongoing work in the area of antimicrobial resistance.
IDERHA: Integration of Heterogeneous Data and Evidence towards Regulatory and HTA Acceptance
In recent years, there has been an exponential growth in the generation of data that could be harnessed for use in healthcare delivery and research. However, accessing, integrating, and analysing these data to maximise their value for patient care and research is extremely challenging.
IDERHA aims to create a scalable platform for the seamless integration or linkage of diverse data at scale to support healthcare professionals, patients, and researchers with new capabilities to improve patient outcomes. With an initial focus on Lung Cancer, the project aims for its outputs to be applicable across multiple disease settings in the future.
NICE is leading on tasks focused on engaging key internal and external stakeholder to develop consensus on policy recommendations to improve both access to data and the acceptability of heterogenous evidence for regulatory and HTA use.