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Severe sialorrhoea (drooling) in children and young people with chronic neurological disorders: oral glycopyrronium bromide

  • Evidence summary
  • Reference number: ES5
  • Published:  14 February 2017

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References

Mier RJ, Bachrach SJ, Lakin RC et al. (2000) Treatment of sialorrhea with glycopyrrolate: a double-blind, dose-ranging study. Archives of Pediatrics and Adolescent Medicine 154: 1214–8

Zeller RS, Lee HM, Cavanaugh PF et al. (2012a) Randomized phase III evaluation of the efficacy and safety of a novel glycopyrrolate oral solution for the management of chronic severe drooling in children with cerebral palsy or other neurologic conditions. Therapeutics and Clinical Risk Management 8: 15–23

Zeller RS, Davidson J, Lee HM et al. (2012b) Safety and efficacy of glycopyrrolate oral solution for management of pathologic drooling in pediatric patients with cerebral palsy and other neurologic conditions. Therapeutics and Clinical Risk Management 8: 25–32


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