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2 Information about isatuximab

Marketing authorisation indication

2.1

Isatuximab (Sarclisa, Sanofi) is indicated 'in combination with bortezomib, lenalidomide, and dexamethasone, for the treatment of adult patients with newly diagnosed multiple myeloma who are ineligible for autologous stem cell transplant'.

Price

2.3

The list price of isatuximab is £506.94 per 100 mg/5 ml vial and £2,534.69 per 500 mg/25 ml vial (excluding VAT; BNF online accessed May 2025).

2.4

The company has a commercial arrangement. This makes isatuximab available to the NHS with a discount and it would have also applied to this indication if isatuximab had been recommended. The size of the discount is commercial in confidence.

Carbon Reduction Plan

2.5

Information on the Carbon Reduction Plan for UK carbon emissions for Sanofi will be included here when guidance is published.