Metastatic malignant disease of unknown primary origin in adults: diagnosis and management

Topic area: cancer diagnosis and treatment

We will not update the diagnostic capabilities of comprehensive genomic profiling for patients presenting with cancer of unknown primary. The population affected is relatively small, and the budget impact is likely to be substantial. There are already capacity challenges in the provision of genomic testing which updated guidance in this area could exacerbate.

We will monitor the ongoing studies in this area and review the topic when these studies are completed.