Nivolumab as neoadjuvant (with chemotherapy) and adjuvant (as monotherapy) treatment for resectable non-small-cell lung cancer [ID6310]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 17 December 2025
Amivantamab with lazertinib for untreated EGFR mutation-positive advanced non-small-cell lung cancer [ID6256]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 11 February 2026
Suspected Cancer: recognition and referral (update)Status:In developmentProgramme:NICE guidelineExpected publication date: 27 March 2026
Catumaxomab for intraperitoneal treatment of malignant ascites in epithelial cellular adhesion molecule-positive carcinomas when further systemic anticancer treatment is unsuitable ID6580Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 30 September 2026
Lurbinectedin with atezolizumab for maintenance treatment of extensive-stage small-cell lung cancer PD [ID6526]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: 2 December 2026
Lung cancer (non-small-cell, advanced or metastatic maintenance treatment) - erlotinib (in combination with bevacizumab) [ID44]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Lung cancer (non-small-cell, advanced or metastatic second line) - erlotinib (in combination with bevacizumab) [ID43]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Cimavax for treating wild-type EGFR-positive non-small-cell lung cancer [1259]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Veliparib with carboplatin and paclitaxel for untreated non-squamous non-small-cell lung cancer [ID1277]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Avelumab for untreated PD-L1 positive recurrent or metastatic non-small-cell lung cancer [ID1261]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Lurbinectedin for treating advanced small-cell lung cancer on or after platinum-based chemotherapy [ID3872]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Pembrolizumab with ipilimumab for treating PD-L1-positive advanced non-small-cell lung cancer [ID3861]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Aumolertinib for untreated EGFR mutation-positive non-small-cell lung cancer [ID4000]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Sugemalimab with chemotherapy for untreated metastatic non-small-cell lung cancer [ID4001]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Cemiplimab with platinum-based chemotherapy for untreated advanced non-small-cell lung cancer [ID3949]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Nivolumab for adjuvant treatment of resected non-small-cell lung cancer [ID4053]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Durvalumab for treating limited-stage small-cell lung cancer after platinum-based chemoradiotherapy [ID5073]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Tiragolumab with atezolizumab for untreated PD-L1-positive advanced non-small-cell lung cancer [ID5122]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Amivantamab with carboplatin and pemetrexed for untreated EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer [ID5110]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Pembrolizumab with stereotactic body radiotherapy for treating unresected stage 1 or 2 non-small-cell lung cancer [ID6149]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Tislelizumab with platinum-based chemotherapy and etoposide for untreated extensive-stage small-cell lung cancer [ID6158]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Encorafenib with binimetinib for treating BRAF V600E mutation-positive advanced non-small-cell lung cancer [ID6177]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Lazertinib with amivantamab and platinum-based chemotherapy for EGFR mutation-positive metastatic non-small-cell lung cancer after a tyrosine kinase inhibitor [ID6305]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Osimertinib for maintenance treatment of EGFR mutation-positive locally advanced unresectable non-small-cell lung cancer after platinum-based chemoradiation [ID6223]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Nivolumab with ipilimumab for untreated unresectable stage 3 non-small-cell lung cancer [ID6248]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Telisotuzumab vedotin for treating c-MET overexpressed, EGFR wild-type, non-squamous advanced non-small-cell lung cancer after 1 or more systemic treatments [ID6253]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Datopotamab deruxtecan for treating advanced non-small-cell lung cancer after platinum-based chemotherapy [ID6241]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Repotrectinib for treating ROS1-positive advanced non-small-cell lung cancer [ID6277]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Durvalumab for adjuvant treatment of resectable non-small-cell lung cancer [ID1263]Status:In developmentProgramme:NICE guidelineExpected publication date: TBC
Pembrolizumab–vibostolimab with etoposide and platinum-based chemotherapy for untreated extensive-stage small-cell lung cancer [ID6361]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Serplulimab with carboplatin and etoposide for untreated extensive-stage small-cell lung cancer [ID6346]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Niraparib with pembrolizumab for maintenance treatment of advanced non-small-cell lung cancer after platinum-based chemotherapy with pembrolizumab [ID6345]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Sacituzumab govitecan for treating advanced non-small-cell lung cancer after platinum-based chemotherapy and a PD-1 or PD-L1 inhibitor [ID6375]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Pembrolizumab–vibostolimab for untreated metastatic non-small-cell lung cancer [ID6365]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Vibostolimab–pembrolizumab for untreated PD-L1-positive metastatic non-small-cell lung cancer [ID6382]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Sotorasib for previously treated KRAS G12C mutation-positive advanced non-small-cell lung cancer (MA review of TA781) [ID6287]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Pembrolizumab with olaparib and chemoradiation for previously untreated limited-stage small-cell lung cancer [ID6412]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Pembrolizumab with chemoradiation, then with or without olaparib, for untreated unresectable locally advanced non-small-cell lung cancer [ID6399]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Retifanlimab with chemotherapy for untreated PD-L1-positive metastatic non-small-cell lung cancer TSID 12007Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Durvalumab for adjuvant treatment of resectable non-small-cell lung cancer [ID1263]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Lorlatinib for ALK-positive advanced non-small-cell lung cancer that has not been treated with an ALK inhibitor [ID6434]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Osimertinib for neoadjuvant treatment of EGFR mutation-positive resectable non-small-cell lung cancer [ID6472]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC
Repotrectinib for treating NTRK fusion-positive advanced solid tumours in people 12 years and over [TSID12147]Status:In developmentProgramme:Technology appraisal guidanceExpected publication date: TBC