Status:
In progress
Technology type:
Medicine
Decision:
Selected
Reason for decision:
Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process:
STA Standard
ID number:
6287

Provisional Schedule

Committee meeting:
12 November 2025
Expected publication:
22 April 2026

Project Team

Project lead
Kate Moore

Email enquiries

If you have any queries please email [email protected]


External Assessment Group:
Kleijnen Systematic Reviews Ltd

Stakeholders

Companies sponsors
Amgen (sotorasib)
Others
Department of Health and Social Care
 
NHS England
Professional groups
Association of Cancer Physicians
 
British Thoracic Oncology Group
 
Cancer Research UK
 
Royal College of Physicians
 
Royal College of Radiologists
Comparator companies
Boehringer Ingelheim (nintedanib) - not participating
 
Bristol-Myers Squibb (adagrasib, subject to NICE evaluation)- not participating
 
Hospira UK (docetaxel) - not participating
 
Seacross Pharmaceuticals (docetaxel) - not participating
General commentators
All Wales Therapeutic and Toxicology Centre
 
British National Formulary
 
Department of Health - Northern Ireland
 
Healthcare Improvement Scotland
 
Medicines and Healthcare Products Regulatory Agency
 
NHS Wales Joint Commissioning Committee
 
Scottish Medicines Consortium
 
Welsh Government

Timeline

Key events during the development of the guidance:

Date Update
14 April 2025 Invitation to participate
24 February 2025 - 25 March 2025 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators
15 March 2024 Please note that following on from information received from the company, which NICE and NHS England must now consider, further information regarding the timelines for this appraisal will be available in due course. In the meantime, NICE will continue to monitor the situation and will provide an update as and when the situation changes.
16 January 2024 - 13 February 2024 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators
16 January 2024 Awaiting development. Status change linked to Topic Selection Decision being set to Selected
16 January 2024 In progress. Draft scope documents issued.

For further information on our processes and methods, please see our CHTE processes and methods manual