Fertility problems: assessment and treatment - update 1 and 2

You can now review and comment on this draft guideline.

The consultation closes on Tuesday 21 October at 5pm.

How to comment

1. Register your organisation or comment as an individual

If you’re commenting for an organisation, your organisation needs to be registered as a stakeholder.

Not eligible? Contact the stakeholder organisation that most closely represents your interests and pass your comments to them.

We can accept comments from individuals. These will be considered, but you won’t get a formal response and they won’t be posted on the NICE website. Wherever possible we encourage you to submit your comments through a registered stakeholder organisation.

2. Read the consultation documents

Documents to comment on:

• Draft guideline
• Evidence review A Ovarian reserve testing
• Evidence review B Subclinical hypothyroidism
• Evidence review C Screening hysteroscopy
• Evidence review D Endometrial receptivity testing
• Evidence review E Ovulation induction strategies
• Evidence review F Cabergoline for hyperprolactinaemia
• Evidence review G Tubal surgery
• Evidence review H Surgery for hydrosalpinges before IVF
• Evidence review I Tubal catheterisation
• Evidence review J Fertility prediction models and IVF access
• Evidence review K Assisted reproduction techniques
• Evidence review L Intracytoplasmic sperm injection
• Evidence review M Advanced sperm selection techniques
• Evidence review N Pre-implantation genetic testing for aneuploidy
• Evidence review O Embryo selection guided by continuous time lapse
• Evidence review P Endometrial scratch
• Evidence review Q Immune therapies
• Evidence review R Fertility preservation
• Evidence review S Sperm DNA fragmentation
• Evidence review T Y chromosome microdeletion
• Evidence review U Hormone treatment for male factor fertility problems
• Evidence review V Treatments for ejaculatory failure
• Evidence review W Surgical interventions for obstructive azoospermia
• Evidence review X Treatments for varicocele
• Evidence review Y Surgical sperm retrieval techniques
• Supplement 1 – Methods
• Supplement 2 – Acknowledgements
• Supplement I – Evidence tables for tubal catheterisation
• Supplement J – Evidence tables for fertility prediction models
• Supplement K– Evidence tables for ART
• Supplement R – Evidence tables for fertility preservation
• Equality and health inequalities assessment (downloadable version)
• Economic model for ART
• Economic model for IVF access

If you want to review the economic model, please see 5. Economic models below and fill in the confidentiality form.

Other information about the consultation

• Committee member list
• Interests register
• Developing NICE guidelines: how to get involved
• Final scope – for information

3. Add your comments

• You must use this Comments form
• You must declare any links with, or funding from, the tobacco industry

If you share similar views with another organisation, send a joint response.

Make sure you consider:

• The areas that will have the biggest impact on practice and be challenging to implement
• How to help users overcome challenges
• Developing NICE guidelines: how to get involved suggests some other areas to comment on.

4. Email the form to us

Email: [email protected]

Deadline: 21/10/2025 at 5pm

5. Economic model

The developer has produced an economic model to support the guideline on Fertility problems: assessment and treatment – update 1 and 2. To receive an executable version of this model, please submit a request to [email protected] with a signed copy of the confidentiality acknowledgement and undertaking form.

We will then send you a link to an executable version of the economic model by email. The deadline for returning your comments is the same as for the guideline consultation: 21/10/2025 at 5pm.