Status:
In progress
Technology type:
Medicine
Decision:
Selected
Reason for decision:
Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Further information:
In appraisal
Process:
STA Standard
ID number:
6291

Provisional Schedule

Committee meeting: 1:
06 January 2026
Expected publication:
18 March 2026

Project Team

Project lead
Leena Issa

Email enquiries

If you have any queries please email [email protected]

Stakeholders

Companies sponsors
AbbVie (venetoclax)
Others
Department of Health and Social Care
 
NHS England
Patient carer groups
Blood Cancer UK
 
Chronic Lymphocytic Leukaemia Support Charity
 
Leukaemia Care
 
Lymphoma Action
Professional groups
Association of Cancer Physicians
 
British Society for Haematology
 
Cancer Research UK
 
Royal College of Physicians
 
Royal College of Radiologists
 
UK CLL Forum
Associated public health groups
None
Comparator companies
AstraZeneca UK (acalabrutinib) (confidentiality agreement signed, participating)
 
Janssen-Cilag (a Johnson & Johnson Innovative Medicine Company) (ibrutinib) (confidentiality agreement signed, participating)
 
Pfizer (rituximab) (confidentiality agreement signed, participating)
 
Baxter Healthcare (cyclophosphamide) (confidentiality agreement not signed, not participating)
 
Celltrion Healthcare UK (rituximab) (confidentiality agreement not signed, not participating)
 
Dr. Reddy's Laboratories UK (bendamustine) (confidentiality agreement not signed, not participating)
 
Roche Products (obinutuzumab, rituximab) (confidentiality agreement not signed, not participating)
 
Sandoz (cyclophosphamide, rituximab) (confidentiality agreement not signed, not participating)
 
Sanofi (fludarabine) (confidentiality agreement not signed, not participating)
 
Seacross Pharmaceuticals (bendamustine) (confidentiality agreement not signed, not participating)
 
Zentiva (bendamustine) (confidentiality agreement not signed, not participating)
General commentators
All Wales Therapeutics and Toxicology Centre
 
British National Formulary
 
Department of Health - Northern Ireland
 
Healthcare Improvement Scotland
 
Medicines and Healthcare products Regulatory Agency
 
NHS Wales Joint Commissioning Committee
 
Scottish Medicines Consortium
 
Welsh Government
Relevant research groups
Institute of Cancer Research
 
Leukaemia UK

Timeline

Key events during the development of the guidance:

Date Update
19 May 2025 Invitation to participate
26 March 2025 - 23 April 2025 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators
18 April 2024 Please note that following on from a request received from the company, which was considered and approved by NICE and NHS England - the timelines for this appraisal have been revised and the appraisal is now anticipated to begin in mid-May 2025 when we will write to you about how you can get involved.
15 February 2024 Please note the draft scope release date is currently TBC and an update will be available in due course
04 January 2024 In progress

For further information on our processes and methods, please see our CHTE processes and methods manual