Suggested remit: To appraise the clinical and cost effectiveness of teprotumumab within its marketing authorisation for treating thyroid eye disease.

Status:
In progress
Technology type:
Medicine
Decision:
Selected
Reason for decision:
Anticipate the topic will be of importance to patients, carers, professionals, commissioners and the health of the public to ensure clinical benefit is realised, inequalities in use addressed, and help them make the best use of NHS resources
Process:
STA Standard
ID number:
6432

Provisional Schedule

Expected publication:
13 August 2025

Project Team

Project lead
Jennifer Upton

Email enquiries

If you have any queries please email [email protected]


External Assessment Group:
Kleijnen Systematic Reviews Ltd

Stakeholders

Companies sponsors
Amgen Limited (teprotumumab)
Others
Department of Health and Social Care
 
NHS England
Patient carer groups
British Thyroid Foundation
 
The Thyroid Trust
Professional groups
Royal College of Ophthalmologists
 
Royal College of Physicians
 
Society for Endocrinology
Associated public health groups
None
Comparator companies
None
General commentators
All Wales Therapeutics and Toxicology Centre
 
British National Formulary
 
Department of Health, Social Services and Public Safety for Northern Ireland
 
Healthcare Improvement Scotland
 
Medicines and Healthcare products Regulatory Agency
 
NHS Wales Joint Commissioning Committee
 
Scottish Medicines Consortium
 
Welsh Government
Relevant research groups
None

Timeline

Key events during the development of the guidance:

Date Update
02 July 2025 - 23 July 2025 Draft guidance: 1
03 June 2025 Committee meeting
03 April 2025 Declaration of interests
29 October 2024 Invitation to participate
18 July 2024 - 15 August 2024 Consultation on suggested remit, draft scope and provisional stakeholder list of consultees and commentators: 6432
18 July 2024 In progress. Scoping commenced.
10 April 2024 Awaiting development. Status change linked to Topic Selection Decision being set to Selected

For further information on our processes and methods, please see our CHTE processes and methods manual