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  • Question on Consultation

    Are the population and subgroups appropriate and described correctly?

  • Question on Consultation

    Are the interventions described correctly?

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    Are there any other technologies that should be included in the assessment?

  • Question on Consultation

    Have the care pathway and comparator been appropriately described?

  • Question on Consultation

    Is the place of the technologies in the pathway described appropriately?

  • Question on Consultation

    Are livers typically split at paediatric liver transplant centres?

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    Are all of the outcomes suitable for inclusion in the assessment?

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    Are there any additional outcomes which should be included, particularly for children and young people?

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    Which outcomes are most relevant to children and young people?

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    Are there any other patient issues that should be considered?

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    Are there any other issues for the implementation and adoption of ex-situ machine technologies for liver transplants?

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    Are there any changes that need to be made to the scope to eliminate unlawful discrimination and promote equality?

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    Are there any additional potential equality or discrimination issues associated with this topic that need to be considered?
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Ex-situ machine perfusion devices for deceased donor liver transplants

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1 Introduction

The use of ex-situ machine perfusion technologies for the preservation and evaluation of liver transplants from deceased donors has been identified by the NICE prioritisation board for assessment. This document describes the context and scope of the assessment. The final scope was informed by discussions at the scoping workshop held on 10th July 2025.

A list of abbreviations is provided in appendix A.