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  • Question on Consultation

    Are the population and subgroups appropriate and described correctly?

  • Question on Consultation

    Are the interventions described correctly?

  • Question on Consultation

    Are there any other technologies that should be included in the assessment?

  • Question on Consultation

    Have the care pathway and comparator been appropriately described?

  • Question on Consultation

    Is the place of the technologies in the pathway described appropriately?

  • Question on Consultation

    Are livers typically split at paediatric liver transplant centres?

  • Question on Consultation

    Are all of the outcomes suitable for inclusion in the assessment?

  • Question on Consultation

    Are there any additional outcomes which should be included, particularly for children and young people?

  • Question on Consultation

    Which outcomes are most relevant to children and young people?

  • Question on Consultation

    Are there any other patient issues that should be considered?

  • Question on Consultation

    Are there any other issues for the implementation and adoption of ex-situ machine technologies for liver transplants?

  • Question on Consultation

    Are there any changes that need to be made to the scope to eliminate unlawful discrimination and promote equality?

  • Question on Consultation

    Are there any additional potential equality or discrimination issues associated with this topic that need to be considered?
The content on this page is not current guidance and is only for the purposes of the consultation process.

Ex-situ machine perfusion devices for deceased donor liver transplants

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10 Other issues for consideration

The longer preservation periods enabled by some machine perfusion technologies may contribute to more environmentally sustainable liver donation and transplantation practices by reducing reliance on time critical logistics compared to SCS, for example by allowing more livers to be transported in the UK by road rather than plane.  

Variations in the provision of ex-situ machine perfusion devices across liver transplant centres could lead to inequities in the allocation of livers, potentially favouring centres with greater capacity for machine perfusion.

Increased use of ex-situ machine perfusion devices may affect the National Liver Offering Scheme (NLOS) and National Organ Retrieval Services (NORS) in ways not currently clear.

The commissioning and policy framework for liver donation and transplantation services varies across the devolved UK health systems. Implementation of recommendations will need to be considered by key national organisations involved in delivering the services.